The New Standard of Care

Why Genetic Testing?                                                    

Specific genes, chromosomes, enzymes and proteins determine drug response.

Genetic testing makes it possible to know a priori how cardiac patients will metabolize a specific drug.  Recent clinical studies reveal that approximately 30% of all patients treated with clopidogrel (Plavix), using standard doses do not respond well to drug therapy due to predetermined genetic factors, thus increasing a patient’s risk to possible adverse cardiovascular events.  Other drugs, such as warfarin (Coumadin) with narrow therapeutic response ranges and beta blockers (Propranolol-Inderal) have similar metabolizing issues—and proper dosing is critical.  Having the genetic cardiac diagnostic test enables you to define drug therapies that are likely to work best for the patient—and produce fewer adverse effects.  These tests also identify a number of inherited genetic variants that increase a patient’s susceptibility to hyperlipoproteinemia, thrombosis and inherited thrombophilia, which is useful information to have prior to an intervention or beginning drug therapy.

Personalized Medicine—The Time is Now              

The use of modern pharmacogenomics enables clinicians to identify key genetic metabolic markers that determine their patient’s metabolism and therapeutic response to a particular drug before prescribing a therapy.  Molecular diagnostics are good for the patient, good for the practice and good for the healthcare system.

Providing cardiology molecular diagnostic (MDx) test services in your office are—simple to perform and easy to get started.  All that is required is:

A lab technologist prepares DNA sample for analysis.

  1. the physician orders the one-time study for the patient;
  2. a nurse or PA obtains a patient specimen by taking either a small blood sample or a buccal swab from the inside of the patients cheek;  and
  3. the patient test sample is sent via prepaid FEDEX envelope to our CLIA-accredited molecular diagnostic lab (Bio Med  Laboratory) for analysis.

A genetics4you™ MDx cardiac panel analysis consisting of eight assays is performed using state-of-the-art microarray DNA analyzers.  The patient’s lab results are provided via fax or electronically to the ordering physician in approximately one week. The ordering physician renders a professional interpretation of the patient’s laboratory results and defines a ’tailored’ or personalized treatment plan—specific to an individual patient.